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Clinical trial

Mindfulness-based Psilocybin Therapy for PTSD

Anthony P KingRecruitingPhase 2Started Jul 1, 202630 enrolledUnited StatesNCT07104916

Abstract

The goal of this study is to learn how psilocybin delivered with mindfulness-based therapy may help symptoms of posttraumatic stress disorder (PTSD). This is an assessor-blinded, randomized, controlled study in participants with PTSD. The study will investigate the changes in brain activity, connectivity, and microstructural neuroplasticity assessed using EEG/EMG and multimodal MRI measures after administration of one oral dose of psilocybin, accompanied either with standard "psychological support" only; or with standard support plus Mindfulness-based Cognitive Therapy (MBCT).

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

PsilocybinDepressionPTSD

Keywords

Psychedelicfunctional MRIMindfulness-based Cognitive Therapymicrostructural neuroplasticityPost Traumatic Stress DisorderDepression - Major Depressive Disorder

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