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Clinical trial

Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies

Beth Israel Deaconess Medical CenterCompletedStarted Feb 28, 202370 enrolledUnited StatesNCT05279898

Abstract

In the PATHFINDER 2 trial, the study investigators will test the intraoperative EEG-guided multimodal general anesthesia (MMGA) management strategy in combination with a postoperative protocolized analgesic approach to: 1. reduce the incidence of perioperative neurocognitive dysfunction in cardiac surgical patients 2. ensure hemodynamic stability and decrease use of vasopressors in the operating rooms 3. reduce pain and opioid consumption postoperatively

Topics & conditions

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KetaminePain

Keywords

Postoperative DeliriumHemodynamic InstabilityNeurocognitive Dysfunction

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