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Clinical trial

Postoperative Opioid-Sparing Effect of a Pecto-Intercostal Fascial Block and Opioid-Free Anesthesia.

Algemeen Stedelijk ZiekenhuisUnknownStarted May 1, 202164 enrolledNCT04854577

Abstract

The present study aims to assess the difference in postoperative opioid consumption between patients who intraoperatively receive a pecto-intercostal facial block combined with opioid-free anesthesia versus a traditional opioid-based regimen for cardiac surgery. The literature on opioid-free anesthesia for cardiac surgery is minimal and solely consists of case reports and retrospective studies. Nevertheless, these reports show the feasibility of opioid-free anesthesia. The purpose of this study is to assess the opioid-sparing effect and efficacy of combining an opioid-free anesthetic regimen with a pecto-intercostal fascial plane block (PIFB) in patients undergoing cardiac surgery. We hypothesize that opioid-free cardiac anesthesia with an intraoperative PIFB significantly reduces postoperative opioid consumption in comparison to a high-dose opioid intraoperative regimen.

Topics & conditions

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KetamineAddiction

Keywords

Analgesics, OpioidAnestheticsCentral Nervous System DepressantsDexmedetomidineEsketamineLidocaineRopivacainePecto-Intercostal Fascial Plane BlockPhysiological Effects of DrugsPeripheral Nervous System AgentsOpioid Free AnaesthesiaOpioid Anaesthesia

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