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Clinical trial

Alleviating Suicidality by Combining Psychotherapy and IM Ketamine for Rapid Treatment in the Emergency Department

The University of Texas Health Science Center at San AntonioRecruitingPhase 2Started Sep 30, 2026200 enrolledUnited StatesNCT07868913

Abstract

Participants are asked to take part in this research study after coming to the Emergency Department with thoughts or behaviors of seriously hurting themselves. There are very few resources to treat acute suicidal thoughts or behaviors in an emergency department. The purpose of this study is to evaluate the effectiveness of combining an intramuscular (IM) injection of ketamine and Crisis Response Planning (CRP), a single, 45-60 minute psychological intervention with a therapist, to quickly reduce suicidal thoughts in patients treated in an emergency department (ED) prior to being admitted to the hospital.

Topics & conditions

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Ketamine

Keywords

PsychotherapyCrisis Response PlanningIntramuscular ketamineEmergency departmentSuicidal Ideation

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