Clinical trial

Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets

University of Texas Southwestern Medical CenterCompletedPhase 2Started May 5, 2022104 enrolledUnited StatesNCT05046184

Abstract

The study is investigating dysfunctions in neurocircuitry in regards to irritability with healthy controls (HC) and individuals with Major Depressive Disorder (MDD) by performing MRIs. The MDD group will also be randomized to receive ketamine or midazolam to investigate changes post-treatment in neurocircuitry with regards to irritability.

Topics & conditions

Detected automatically by Psychedelic Commons from the title and abstract, not labels from the source. They may be incomplete.

KetamineDepression

Keywords

major depressive disorderMDDdepressive disorderdepression symptomshealthy controlsirritabilityMajor Depressive DisorderHealthy Controls

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