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Clinical trial

Consciousness and Psilocybin Effects on Well-Being: The CoPEWell Study

University of Wisconsin, MadisonNot yet recruitingPhase 1Started Oct 1, 2026120 enrolledUnited StatesNCT07360301

Abstract

This study is exploring how psilocybin (a psychedelic drug) may improve mood and wellbeing. Many people report feeling better after taking psilocybin, but it is not clear why. The CoPEWell study will test whether these improvements come from the psychedelic experience itself (the "trip") or from direct effects on the brain. To study this, up to 120 participants will be enrolled to receive psilocybin either while awake or asleep and can expect to be on study for up to 4 months.

Topics & conditions

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Psilocybin

Keywords

Well-Being, PsychologicalPsychedelic Experiences

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