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Clinical trial

Ketamine As an Adjunctive Therapy for Major Depression (2)

University of Dublin, Trinity CollegeCompletedPhase 3Started Sep 13, 202163 enrolledIrelandNCT04939649

Abstract

Pragmatic, randomised, controlled, parallel-group, superiority trial of ketamine vs. midazolam as an adjunctive therapy for depression. The main purpose of the trial is to assess the mood-rating score difference between ketamine and midazolam from before the first infusion to 24 hours after the final infusion, supplemented by a 95% confidence interval. There will also be a 24-week follow-up after the final infusion session.

Topics & conditions

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KetamineDepression

Keywords

glutamateMajor Depressive EpisodeUnipolar DepressionBipolar Depression

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