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Esketamine for Treatment of Cognitive Decline in Alzheimer’s Disease: Systematic Review of Pre-clinical and Clinical Studies

OSFJul 19, 2025

Abstract

A systematic review of preclinical and clinical evidence that esketamine may hold potential to alleviate cognitive decline associated with Alzheimer’s disease and the possible mechanistic pathways.

Topics & conditions

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Ketamine

Keywords

Alzheimer’s diseaseCognitionEsketaminePsychedelicsSystematic Reviews

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