The open index of psychedelic research

Environmental and Endogenous Psychedelics as Adaptive Plasticity Modulators: An Integrative Systems Biology Framework

Genc, Kaya, John, Silas Njiru, Barkell, James

Reconstructing Scientific Knowledge: A Multidimensional Framework for Understanding Evidence, Causality, and Observable Phenomena in Objective Reality

Genc, Kaya, John, Silas Njiru, Barkell, James

Supporting dataset for structure-based molecular modeling of S-Remiketamine and derived arylcyclohexanone analogues

Metwally Alkhatip, Ahmed Abdelaal Ahmed Mahmoud, Raza, Usama

DatasetAyahuasca

Data from: Comparative chromosome-scale genomics of the ayahuasca liana Banisteriopsis caapi reveals paleopolyploid ancestry and recent tandem-gene expansions as candidate signatures of ethnovariety differentiation

Varani, Alessandro, Prosdocimi, Francisco

Near-Death Experience Phenomenology in Ketamine and Psychedelic Research: A Curated Literature Dataset

Alvear, Michael

DatasetMDMA

MDMA restores cortico-accumbal signaling and rescues autism-related social deficits.

Llorach, Pierre, Kodali, Anish, Hertweck, Caroline +4

An integrated living dataset of psilocybin and psilocin publications, preprints, and trial records

Germann, Christopher B.

The SAIPIENT Study – Spirituality and AI: Psychology, Identity, Emergence and New Theologies

Pollak, Thomas, Palitsky, Roman, Evans, Jules +4

Supporting Data and Regulatory Analysis Tools for the Assessment of Psychedelic Clinical Trials

Swieczkowski, Damian

Music in Psychedelic- and Ketamine-Assisted Therapy: A Curated Evidence Map, 1967–2026

Alvear, Michael

Data from: <em>In vivo</em> changes in zebrafish anesthetic sensitivity in response to the loss of kif5Aa are associated with the alteration of mitochondrial motility

Victoria Bedell, Roderic Eckenhoff

DatasetIbogaine

Tuning reductase activity in monoterpene indole alkaloid biosynthesis

Sarah O'Connor

DatasetDMT

HaD-PET: Effects of DMT and harmine on cerebral glucose metabolism: FDG-PET dataset

Klemens Egger, Milan Scheidegger, Paul Cumming

OpenNeuro2026

Oral Ketamine for Depression: A Structured Evidence Table of Dosing Regimens, Clinical Outcomes, and Adverse Events

Alvear, Michael

ANESTHETIC CHALLENGE IN A PATIENT WITH COMPRESSIVE CERVICAL CHORDOMA: A CASE REPORT

Hassan Kraitiss , Yasser Ouatab , Marouane Jidal , Reda Amahroq , Youssef Halhoul , Aziz Benakrout and Mustapha Bensghir

Aggregate Dataset for Reddit Discussions of Oral and Sublingual Ketamine Therapy

Alvear, Michael

Drug-induced changes in connectivity to midbrain dopamine cells revealed by rabies monosynaptic tracing

Katrina Bartas, Pieter Derdeyn, Guilian Tian +5

Processed Data - Single-nucleus transcriptomics reveals time-dependent and cell-type-specific effects of psilocybin on gene expression

Liao, Clara, O'Farrell, Ethan, Weiner, Amanda +5

Analysis Code and Results: Granger-Predictive Influence Pipeline Across Five Pharmacological fMRI Datasets (LSD, Psilocybin, DMT, Ketamine, Propofol)

malone, ryan

Claim Verification: "Critical periods of heightened cortical plasticity close permanently after early development, rendering the adult brain largely incapable of experience-dependent reorganization comparable to juvenile levels." — Disproved

Proof Engine

Data from: Psilocin fosters neuroplasticity in iPSC-derived human cortical neurons

Malin Schmidt, Anne Hoffrichter, Mahnaz Davoudi +7

When the psychedelic state's over: limited evidence for persistent neurophysiological changes in experienced psychedelic users

Wójcik, Maja, Orłowski, Paweł, Adamczyk, Stanisław +4

AI-Powered Prediction of Psilocybin Production from Microscopy Images of Aspergillus nidulans in Stirred-Tank Reactors

Akbarimoghaddam, Parastoo, Weiser, Sophie, Svensson, Carl-Magnus +5

Deconvolved Wide-Field Calcium of Mouse Cortex with Sub/Supra-anesthetics doses of Isoflurane, Ketamine, and Pentobarb.

Curic, Davor