The open index of psychedelic research

Patient selection and safety of lidocaine-esketamine analgesia after hepatectomy.

Yu H, Lyu H

Lidocaine-esketamine analgesia after hepatectomy: a reply.

Xu Y, Jiang C, Sessler DI

Ego Dissolution or Self-Expansion? A Relational Reframing of Psychedelic Self-Experience

Amarante J

Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants

Efficacy and Safety of Psychedelic Microdosing on Psychological Outcomes in Healthy Adults: A Systematic Review and Meta-analysis.

Meshkat S, Leung M, Meshkat S +13

Mystical and Affective Features of Naturalistic Psychedelic Experiences: Dataset and Supplementary Materials

Milczanowski, Aleksander

Ketamine assisted psychotherapy to reduce chronic neuropathic pain: A mixed-methods randomized pilot trial.

Goel A, Diep C, Zahin A +16

Ibogaine as a double-edged sword: Developmental cardiotoxicity and neurobehavioral alterations in zebrafish.

de Oliveira AL, Abe FR, Dos Santos RG +2

A contemporary exploration of motivations and practices of psychedelic use among emerging adult cannabis users in the United States: A qualitative analysis.

Conn BM, Osornio A, Sheean K +6

Psilocybin-Assisted Therapy in Psychiatry: A Narrative Clinical Review of Mechanisms, Therapeutic Applications, and Emerging Evidence (2025-2026).

Anghel T, Cojocaru A, Hogea L +5

Preclinical Comparison of DMT and 5-MeO-DMT Reveals Behavioral Dissociation, Distinct TrkB Activation and Differential Plasticity Profiles

Shahar O, Botvinnik A, Chaykin M +7

MDMA-Enhanced Exposure Therapy Reverses PTSD-Like Features In a Learned Helplessness Mouse Model

Shahar O, Golding P, Chaykin M +4

Psilocybin Administration With 5-HT1a Blockade

Investigating the Effects of Psilocybin on Cognitive Flexibility in Touchscreen and Naturalistic Variations of the Probabilistic Reversal Learning Task

Anderson D, Maillot N, Thomas CW +3

Real-world use, safety, and mental health efficacy of regulated psilocybin services in Oregon and Colorado

Thompson SM, Effinger DP, Novick AM +5

Psychedelic integration beyond the verbal: participatory-imaginal processing as a hypothesis-generating therapeutic framework.

Back AL, Bosnak R

Improving Psychedelic Harm Reduction and Therapy: Community Perspectives from Individuals Who Use Recreationally and for Mental Health Purposes.

Jewell JS, James C, Black JC

Opposite network patterns of integration-segregation in psychedelic and sedated states of consciousness.

Dai R, Jang H, Hudetz AG +2

Effects of naturalistic psychedelic use on executive functioning: An online survey of lifetime history and recent use in university students.

Todesco S, Allan Z, Liu MYM +1

Low-dose esketamine for postoperative pain, sleep, and hemodynamic stability in functional endoscopic sinus surgery: a retrospective cohort study.

Zhao YP, Fu XS, Jia Y +2

Psychedelics and astrocytes: a hypothesis-driven perspective on neuro-glial integration, network plasticity, and neuroimmune reprogramming.

Ke X, Du X, Wang X

Efficacy of intravenous ketamine for neuropathic pain: a systematic review and meta-analysis of randomized clinical trials.

Leão Nunes Filho MJ, Barreto ESR, Antunes Júnior CR +7

Direct anti-inflammatory actions of <i>N,N</i> -dimethyltryptamine on microglia are revealed by proteomic profiling and receptor pharmacology

Pesti I, Bessenyei Á, Frank R +12

Exploring Ketamine in Traumatic Brain Injury: A Narrative Review of Its Current Emerging Perspectives from Clinical and Preclinical Studies.

Alaifan T, Khojah AM, Sakhakhni A +7