The open index of psychedelic research

Bidirectional control of vesicular GABA release, LTP, and amotivation by GluN2D-selective allosteric modulators and ketamine.

Oláh VJ, Witteveen IF, Banke TG +32

MDMA as an early post-trauma intervention in a translational animal model of PTSD.

Baruch O, Reiss N, Todder D +2

Ketamine in neurosurgery: a historical perspective.

Sinclair AL, Jelkin G, Zucca B +2

Investigating the effects of chlorogenic acid on novel object recognition memory impairment, hyperlocomotion, and prefrontal BDNF expression in a sub-chronic ketamine-induced schizophrenia-like rat model.

Bahrami A, Ghorbani Yekta B, Baghdasarians A

Comparative Electrocorticographic Signatures of <i>S</i>‑Ketamine and Racemic Ketamine in the Rat Visual Cortex Across Temporal Phases.

Lins A, Eiró-Quirino L, de Souza LV +11

The varieties of integration processes: Four pathways following psychedelic and other exceptional experiences

Adams J, Michael P, Luke D

The psychedelic DOI decreases the modularity of the cortical network by increasing cortico-cortical and thalamo-cortical functional influence

Doronin R, Stroukov E, Keller GB

Distinct correlates of growth and enduring difficulty after psychedelic experiences: A cross-sectional analysis of the Global Psychedelic Survey 2025

The impact of different intervention methods (anesthetic adjuvant drugs, anesthetic techniques, and non-pharmacological interventions) on postoperative cognitive function in patients undergoing cardiac surgery: a systematic review and Bayesian network meta-analysis.

Xue J, Wang X, Qiu Y

Wastewater-based assessment of episodic changes in psychoactive compounds and hormones during music festivals.

Tulipánová A, Mackuľak T, Horáková I +8

No evidence for deleterious effects of psilocybin and MDMA on working memory or related neurophysiological activity in a non-clinical population: An uncontrolled exploratory study.

Bailey NW, Webb SL, Fitzgibbon BM +13

Estimating Cardiac 5-HT2B Safety Margins for Repeated Low-Dose Psilocybin Using an Exposure–Response Model

Tyler WJ, Sellers E, McDonnell MB

Obstetric anesthesia and postpartum mental health: implications from delivery to long-term recovery.

Lee SH, Kwak KH

Reporting Quality in Randomized Controlled Trials Evaluating Psilocybin-Assisted Therapy for Major Depressive Disorder: A Systematic Review

A Study of Esketamine Nasal Spray Versus Placebo Spray in Adult Participants With Treatment-resistant Depression

Efficacy of intraoperative low dose intravenous Esketamine for acute postoperative pain control: Meta-analysis of randomized controlled trials.

Majeed E, Rafique I, Inam K +1

Rapid clinical and EEG microstate changes 24 h after intranasal esketamine in major depressive disorder with suicidal ideation: a prospective paired study.

Gu T, Zhang J, Wang R +10

Dissociation and antidepressant response to subcutaneous esketamine: A clinical study.

Gonçalves KTDC, Tavares VDO, Palhano-Fontes F +12

Comparing synthetic and biological therapy for the treatment of cluster headache: what is needed and when?

Parr BA, Young WB, Silberstein SD

Cellular mechanisms of serotonergic psychedelics - apical hypercontextualisation.

Kaup KK, Jiménez JH, Aru J

Effects of low-dose esketamine on early quality of recovery following minimally invasive esophagectomy: a multicenter, randomized controlled study.

Zhang H, Yin F, Li L +8

Dynamic Substates of the Default Mode Network Are Associated with Mystical Experiences and Clinical Outcomes after Magnesium-Ibogaine Treatment in Veterans with Traumatic Brain Injury

Shinozuka K, Olash C, Han T +16

Ketamine abuse also affects sexual health.

Leerssen ECM, van der Sanden WMH, de Kemp VF +3

Longitudinal neural and psychological changes following psilocybin under compassion imagery priming.

Pallavicini C, Llobenes L, Cavanna F +14