Chen Y

Response to "Methodological Caveats in Evaluating Perioperative Esketamine for Postoperative Pain Sensitivity: A Comment on the Study by Chen et al" [Response to Letter].

Wu Y, Chen Y

Observational study on the application of different esketamine gargle doses for the prevention of postoperative sore throat after laryngeal mask airway insertion.

Bo L, Chen Y, Sun L +4

ArticleLSD

Targeting peripheral 5-HT<sub>2A</sub>R enhances antitumor immunity in colorectal cancer.

Wen Y, Tang L, Duan W +22

The application of esketamine in cancer-related depressive states: attention from mechanisms to clinical translation.

Chen L, Chen Y, Zhao Y +7

Acute Effects of Esketamine on the EEG Power Spectrum and Signal Complexity in Prolonged Disorders of Consciousness: A Prospective Exploratory Cohort Study.

Liang Y, Yang W, Wang X +8

A Study on the ED90 of Esketamine Combined with Ropivacaine for Early Epidural Analgesia During the First Stage of Labor in Nulliparous Women: A Randomized, Sequential Dose-Finding Trial.

Lin X, Tu Y, Qiu P +3

Effect of Subanesthetic Doses of Esketamine on Early Postoperative Pain Sensitivity in Patients Undergoing Salpingectomy: A Randomized Clinical Trial.

Wu Y, Wu H, Dong J +11

Impact of esketamine-based opioid-free anesthesia on quality of recovery after laparoscopic hysterectomy: a randomized controlled trial using the QoR-40 questionnaire.

Chen Y, Qin P, Tian E +3

Anesthesia management of a child with Melnick-Needles syndrome associated with retrognathia and significant tracheomalacia.

Li X, Chen Y, Zuo Y

Esketamine attenuates bone cancer pain by suppressing MAPK signaling and glial activation in the spinal dorsal horn of rats.

Cheng L, Wang D, Zhang Z +9

Impact of Combining Esketamine With Erector Spinae Plane Block on Opioid Consumption, Inflammatory Stress, and Cognitive Function After Thoracoscopic Surgery.

Zhu J, Chen Y, Shu L +4

ArticlePsilocybin

Structure-Guided Design of Novel 5-HT<sub>2A</sub> Partial Agonists as Psychedelic Analogues with Antidepressant Effects.

Li R, Yan H, Chen Y +7

Validation and clinical application of the Chinese version of the rapid response scale.

Chen Z, Shen J, Chen Y +7

A comparative study of dexmedetomidine combined with esketamine and sufentanil for sedation and analgesia in patients undergoing microwave ablation of lung tumors: A prospective single-center randomized double-blind clinical trial.

Li Y, Li Y, Zhang Y +6

ArticleLSD

[Establishment and application of a high-throughput screening method for drugs targeting the 5-hydroxytryptamine 2A receptor based on cellular calcium flux signals].

Zhang B, Shi J, Zhang Y +4

Microglial BDNF modulates arketamine's antidepressant-like effects through cortico-accumbal pathways.

He L, Wang X, Luo S +8

PreprintKetamine

Validation and Clinical Application of the Chinese Version of Rapid Response Scale

Chen Z, Shen J, Chen Y +7

Effects of Esketamine Versus Remifentanil on Hemodynamics and Prognosis in Patients with Septic Shock Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial.

Li Y, Li H, Zhang F +2

ArticleMDMA

Mitochondrial Calcium Uniporter (MCU)-Mediated Calcium Overload in Psychoactive Drug Neurotoxicity: From Pathogenesis to Therapeutic Targets.

Yang X, Chen Y, Zheng G +2

Effect of Different Doses of Esketamine on Postoperative Recovery in Patients Undergoing Gynecologic Laparoscopic Surgery, a Randomized, Double-Blind, Single-Center Clinical Study.

Li T, Han L, Wu Z +2

Effects of the subanesthetic dose of esketamine on postoperative sleep quality in patients undergoing modified radical mastectomy: a randomized, double-blind controlled trial.

Chen Y, He J, Huang R +3

The Opioid-Sparing Effects of Intraoperative Esketamine Combined with Dexmedetomidine During Laparoscopic Major Abdominal Surgery: A Randomized Controlled Double-Blind Trial.

Wang W, Chen Y, Li G +4

Effect of esketamine on postoperative sleep disturbance in patients undergoing spinal surgery: a study protocol for a randomised, double-blinded, placebo-controlled clinical trial.

Jian M, Chen Y, Wang S +5

The effect of esketamine combined with sufentanil based patient-controlled intravenous analgesia for postoperative pain in patients undergoing third molar surgery and maxillofacial trauma: a randomized clinical trial.

Li X, He X, Li M +4

Effect of esketamine on postoperative delirium in general anesthesia patients undergoing elective surgery: a meta-analysis of randomized controlled trials.

Zhang W, Wang D, Li S +2

Impact of different doses of esketamine on the incidence of hypotension in propofol-based sedation for colonoscopy: a randomized controlled trial.

Fu M, Sheng B, Liu R +8

A real-world pharmacovigilance study of esketamine nasal spray.

Chen Y, Gu H, Li W +1

Exploring the Analgesic Efficacy and mechanisms of low-dose esketamine in pregnant women undergoing cesarean section: A randomized controlled trial.

Zhang J, Sun D, Wang J +5

ArticlePsilocybin

Psilocybin desynchronizes the human brain.

Siegel JS, Subramanian S, Perry D +30

Perioperative Adjunctive Esketamine for Postpartum Depression Among Women Undergoing Elective Cesarean Delivery: A Randomized Clinical Trial.

Chen Y, Guo Y, Wu H +7

Postoperative esketamine improves ventilation after video-assisted thoracoscopic lung resection: A double-blinded randomized controlled trial.

Fu M, Xu R, Chen G +5

ArticlePsychedelics

Feasibility and effectiveness study of applying a hallucinogen harm reduction and integration model to a mindfulness thinking intervention using virtual reality: A randomized controlled trial.

Chen Y, Wang T, Tan Y +1

Efficacy of intraoperative subanesthetic dose of ketamine/esketamine in preventing postoperative cognitive dysfunction: a systematic review and meta-analysis.

Zhou N, Chen C, Liu Y +2

Opioid-Free Versus Opioid-Based Anesthesia on Postoperative Pain After Thoracoscopic Surgery: The Use of Intravenous and Epidural Esketamine.

Yan H, Chen W, Chen Y +11

Esketamine ameliorates post-stroke anxiety by modulating microglial HDAC3/NF-κB/COX1 inflammatory signaling in ischemic cortex.

Huang A, Chen Y, Wang S +13

Safety and tolerability of esketamine in propofol based sedation for endoscopic variceal ligation with or without injection sclerotherapy: Randomized controlled trial.

Chen Y, Chen J, Wang Q +7

ArticlePsilocybin

Rearing behaviour in the mouse behavioural pattern monitor distinguishes the effects of psychedelics from those of lisuride and TBG.

Chen Y, Liu J, Yao Y +2

Esketamine Anesthetizes Mice With a Similar Potency to Racemic Ketamine.

Ma X, Peng J, Chen Y +4