Kwan AC

Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA; Department of Psychiatry, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: alex.kwan@cornell.edu.

Kwan AC

Serotonin biology as a basis for explaining psychedelic drug action.

Psychedelic drug action at dendrites is gated by behavioral state and serotonin receptors

α&lt;sub&gt;2&lt;/sub&gt;-Adrenergic receptor modulates 5-HT&lt;sub&gt;2A&lt;/sub&gt;-mediated behavioral effects of MDMA and psilocybin in mice.

Structural plasticity and enhanced fear extinction following psilocybin in chronically stressed mice

Psilocybin reshapes cortical inhibition through selective interneuron recruitment

Enhancing cGMP signaling with psilocybin reduces head twitch and restructures the synaptic proteome while maintaining antidepressant response

Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks.

Psychedelic studies in nonhuman primates: Past and future.

The ABCs of psychedelics: a preclinical roadmap for drug discovery.

Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks

Psilocybin Prolongs the Neurovascular Coupling Response in Mouse Visual Cortex

Psilocybin's lasting action requires pyramidal cell types and 5-HT&lt;sub&gt;2A&lt;/sub&gt; receptors.

Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression.

Single-nucleus transcriptomics reveals cell type-specific and time-dependent effects of psilocybin and ketamine on gene expression

Structural neural plasticity evoked by rapid-acting antidepressant interventions.

Pyramidal cell types and 5-HT <sub>2A</sub> receptors are essential for psilocybin’s lasting drug action

Ventral hippocampal parvalbumin interneurons gate the acute anxiolytic action of the serotonergic psychedelic DOI.

Psilocybin Facilitates Fear Extinction: Importance of Dose, Context, and Serotonin Receptors.

Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression

Psilocybin facilitates fear extinction: importance of dose, context, and serotonin receptors

5-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in mice.

Shared and Distinct Brain Regions Targeted for Immediate Early Gene Expression by Ketamine and Psilocybin.

5-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in mice

Psychedelics and Neural Plasticity: Therapeutic Implications.

The neural basis of psychedelic action.

Shared and distinct brain regions targeted for immediate early gene expression by ketamine and psilocybin

Psychedelics.

Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo.

A Dendrite-Focused Framework for Understanding the Actions of Ketamine and Psychedelics.

α<sub>2</sub>-Adrenergic receptor modulates 5-HT<sub>2A</sub>-mediated behavioral effects of MDMA and psilocybin in mice.

Psilocybin's lasting action requires pyramidal cell types and 5-HT<sub>2A</sub> receptors.