Wang Y
Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
ArticlePsychedelics
Mechanistic Basis for 5-HT<sub>2A</sub>R Over 5-HT<sub>2B</sub>R Activation.
ArticleDMT
Psychedelic 4-AcO-DMT attenuated looming-induced freezing behaviors by activating PrL <sup>CaMKIIα</sup> neurons in mice.
ArticleKetamine
Interpreting Perineural Esketamine for Analgesia After Total Knee Arthroplasty: Methodological and Reporting Considerations [Response to Letter].
ArticleKetamine
Esketamine Use and Attempted Suicide or Intentional Self-Harm Among Individuals with Treatment-Resistant Depression: A Retrospective Cohort Study.
ArticleKetamine
Esketamine Ameliorates Propofol-Induced Long-Term Cognitive Impairments in Juvenile Rats by Suppressing Autophagy via Activating the PI3K/Akt/mTOR Signaling Pathway.
PreprintKetamine
The Effects of Different Doses of Intravenous Esketamine on Postoperative Sleep and Chronic Pain in Patients Undergoing Thoracoscopic Lung Resection Surgery: A Randomized Controlled Trial
ArticlePsychedelics
Hippocampal synaptic transmission and Ca<sup>2</sup>⁺ signaling are altered by the selective 5-HT<sub>2A</sub> receptor agonist, 25CN-NBOH.
ArticleKetamine
Rapid clinical and EEG microstate changes 24 h after intranasal esketamine in major depressive disorder with suicidal ideation: a prospective paired study.
ArticleKetamine
Esketamine as an Adjuvant to Levobupivacaine in Thoracic Paravertebral Block for Thoracoscopic Lung Cancer Surgery: A Retrospective Propensity Score-Matched Cohort Study.
ArticleKetamine
Effect of opioid-free anesthesia on postoperative recovery in elderly patients undergoing laparoscopic abdominal surgery: a randomized controlled trial.
ArticleKetamine
Ultrasound-Guided Femoral Nerve Block with Esketamine Adjuvant for Postoperative Analgesia in Total Knee Arthroplasty-A Randomized, Double-Blind, Controlled Trial.
ArticleKetamine
Effects of sub-anesthetic doses of esketamine on immune function and postoperative negative emotions in acoustic neuroma patients: a randomized clinical trial.
ArticleKetamine
Mitochondrial-inflammation crosstalk in major depressive disorder: molecular mechanisms and therapeutic implications.
ArticlePsilocybin
Chemical ecology and convergent evolution of natural hallucinogens: From ecological defense to conserved neural targets.
ArticleKetamine
Efficacy and Safety of Ultrasound-Guided Erector Spinae Plane Block at Different Injection Depths for Percutaneous Kyphoplasty: A Randomized Controlled Trial.
ArticleKetamine
Effect of postoperative esketamine on depression after pancreatoduodenectomy: a randomized controlled trial.
ArticleKetamine
Esketamine attenuated sepsis-induced organ injury in mice via the TGF-β-Smad3 signaling pathway.
ArticleKetamine
Esketamine and postoperative cognitive dysfunction in aged mice: Role of the SIRT3/AMPK/mTOR pathway.
ArticleMescaline
The complete chloroplast genome sequence of <i>Lophophora diffusa</i>.
ArticleKetamine
Effect of Dexmedetomidine Combined with Esketamine on Postoperative Fatigue in Patients Undergoing Total Laparoscopic Hysterectomy: A Single-Center Randomized Double-Blinded Controlled Trial.
ArticleKetamine
Neuroprotective Effects of Esketamine in Central Nervous System Disorders: Mechanisms and Cellular Targets.
ArticlePsychedelics
Leveraging molecular dynamics simulations to study psychedelics and their receptors in future drug development.
ArticleDMT
5-HT<sub>2A</sub> receptors in the prelimbic cortex VIP-expressing interneurons: A mechanism for psychedelic-induced innate fear attenuation.
ArticlePsilocybin
Therapeutic effects of psilocybin in major depressive disorder: a systematic review and meta-analysis exploring dose effects.
ArticlePsilocybin
Acute psilocin increased cortical activity in rat.
ArticleDMT
The Mediating Effects of Digital Music Therapy on Depressive Symptoms in Youth During the COVID-19 Pandemic: A Randomized Controlled Trial.
ArticlePsilocybin
Single-dose psilocybin promotes cell-type-specific changes of neurons in the orbitofrontal cortex.
ArticleKetamine
Effects of esketamine on postoperative pain, anxiety, depression, sleep, and inflammation in pregnancies undergoing cesarean section: A randomized controlled trial.
ArticleKetamine
Intranasal esketamine plus dexmedetomidine versus dexmedetomidine alone for emergence delirium in pediatric patients: a systematic review and meta-analysis of randomized controlled trials.
ArticleKetamine
Effect of Anterior Quadratus Lumborum Block at the Lateral Supra-Arcuate Ligament Combined with Esketamine on the Quality of Postoperative Recovery After Laparoscopic Radical Surgery for Elderly Patients with Colorectal Cancer: A Randomized Controlled Trial
ArticleKetamine
Esketamine/Ketamine: Dual-Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology.
ArticleKetamine
Effects of Esketamine-Dexmedetomidine Combination on Immediate Postprocedural Oxygenation Index in Severe Pneumonia Patients Undergoing Bedside Fiberoptic Bronchoscopic Sputum Aspiration: A Prospective Randomised Controlled Trial.
ArticleKetamine
Prefrontal neurophysiological changes associated with subanesthetic esketamine accelerating mice emergence from propofol anesthesia.
ArticleKetamine
Effect of esketamine on postoperative depression and anxiety in patients undergoing cardiac valve surgery: A randomised, placebo-controlled, double-blinded clinical trial.
ArticleKetamine
Different interventions in preventing sufentanil-induced cough: a systematic review and network meta-analysis.
ArticleKetamine
Novel and emerging anesthetic drugs for the treatments of major depression: a comprehensive review of efficacy, mechanism, and outlook.
ArticleKetamine
Letter to the Editor: Comments on the manuscript entitled 'Effect of intraoperative low-dose esketamine on postoperative quality of recovery in patients undergoing laparotomy for gynecologic malignancy: a randomized controlled trial'.
ArticleKetamine
Effect of esketamine as an adjuvant of ropivacaine on the efficacy of supraclavicular brachial plexus block in radius fracture surgery: a randomized controlled trial.
ArticleKetamine
Comparison of opioid-free versus weak-opioid general anesthesia on quality of postoperative recovery in soldiers undergoing arthroscopic meniscal surgery.
ArticlePsychedelics
In Silico Characterization of Bromo-DragonFLY Binding to the 5-HT<sub>2A</sub> Receptor: Molecular Insights Into a Potent Designer Psychedelic.
ArticleKetamine
The Early Effects of Esketamine on the Tumor Metastatic Microenvironment in Postoperative Lung Cancer Patients.
ArticleKetamine
Discovery of Rapid-Acting, Orally Available Antidepressants by Activating TrkB Signaling.
ArticleKetamine
Esketamine for Preventing Catheter-Related Bladder Discomfort After Ureteroscopic Lithotripsy: A Randomized Controlled Trial.
ArticleKetamine
Psychoactive substances: novel molecular insights and therapeutic potential for Alzheimer's disease.
PreprintKetamine
Effects of esketamine on postoperative pain, anxiety, depression, sleep, and inflammation in patients undergoing cesarean section: A randomized controlled tria
ArticlePsychedelics
Reimagining Neuropsychiatric and Neurological Disorders through the Lens of Brain Network Dynamics: Psychedelics as Catalysts for System-Level Plasticity.
ArticleKetamine
Opioid-Free Anesthesia Improved the Quality of Recovery After Thyroidectomy Through Pre-Emptive and Preventive Analgesia: A Randomized Controlled Trial.
PreprintKetamine
Ultrasound-Guided Thoracic Paravertebral Block with Levobupivacaine-Esketamine Combination for Thoracoscopic Lung Cancer Surgery
ArticleKetamine
Esketamine combined with low-dose propofol induction strategy for category-1 cesarean section: a case series.
ArticlePsychedelics
Entheogen: an evolutionary medicine for neuropsychiatric disorders.
ArticleKetamine
Advances in the study of NMDA receptors in depression pathogenesis and the antidepressant efficacy of their antagonists.
ArticleKetamine
Effect of perioperative intravenous ketamine on postoperative sleep disturbance in patients undergoing non-cardiac surgery: A systematic review and meta-analysis.
ArticleLSD
Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential.
ArticleKetamine
Effect of Different Doses of Esketamine on Postoperative Recovery in Patients Undergoing Gynecologic Laparoscopic Surgery, a Randomized, Double-Blind, Single-Center Clinical Study.
ArticlePsychedelics
The Selective 5HT<sub>2A</sub> Receptor Agonist, 25CN-NBOH Exerts Excitatory and Inhibitory Cellular Actions on Mouse Medial Prefrontal Cortical Neurons.
ArticleKetamine
Esketamine alleviates depressive-like behavior in neuropathic pain mice through the METTL3-GluA1 pathway.
ArticleKetamine
Comparative Efficacy of Esketamine vs Sufentanil with Propofol for Sedation in EUS: A Randomized, Controlled Study.
ArticleKetamine
Effects of epidural esketamine versus sufentanil on labor analgesia and postpartum depression: a retrospective cohort study.
ArticleKetamine
Effect of subanesthetic dose of esketamine on early postoperative depression in elderly patients with Sarcopenia.
ArticleKetamine
A Comparative Study of Esketamine-Propofol and Sufentanil-Propofol for Analgesia and Sedation During Breast Minimally Invasive Rotary Resection with Local Anesthesia: A Randomized Double-Blind Clinical Trial.
ArticlePsilocybin
Structural insights into tryptamine psychedelics: The role of hydroxyl indole ring site in 5-HT<sub>2A</sub> receptor activation and psychedelic-like activity.
ArticleKetamine
Effect of different doses of esketamine on the median effective concentration of propofol for inhibiting body movement during hysteroscopy.
ArticlePsilocybin
Neuroprotective effects of psilocybin in a rat model of stroke.
ArticlePsychedelics
Psychedelics and Consciousness: Expanding the Horizons of Mind and Therapy.
ArticleKetamine
Inflammatory cytokines, cortisol, and anhedonia in patients with treatment-resistant depression after consecutive infusions of low-dose esketamine.
ArticleKetamine
Effects of subanesthetic repeated esketamine infusions on memory function and NGF in patients with depression: An open-label study.
ArticleKetamine
Accurate Machine Learning-based Monitoring of Anesthesia Depth with EEG Recording.
ArticleKetamine
The CB2-PKC pathway is involved in esketamine-induced anti-inflammation in BV-2 microglial cells exposed to lipopolysaccharides.
ArticleKetamine
Esketamine alleviates ferroptosis-mediated acute lung injury by modulating the HIF-1α/HO-1 pathway.
ArticleKetamine
Opioid-free anesthesia improves postoperative recovery quality of small and medium-sized surgery: a prospective, randomized controlled study.
ArticleLSD
Structural basis of psychedelic LSD recognition at dopamine D<sub>1</sub> receptor.
ArticlePsilocybin
Efficacy and safety of eight enhanced therapies for treatment-resistant depression: A systematic review and network meta-analysis of RCTs.
ArticleKetamine
Research trends and hotspots of ketamine from 2014 to 2023: a bibliometric analysis.
ArticleKetamine
Pharmacovigilance of esketamine nasal spray: an analysis of the FDA adverse event reporting system database.
ArticleKetamine
The influence of low-dose s-ketamine on postoperative delirium and cognitive function in older adults undergoing thoracic surgery.
ArticleKetamine
Effects of esketamine on postoperative fatigue syndrome in patients after laparoscopic resection of gastric carcinoma: a randomized controlled trial.
ArticleKetamine
Effect of Continuous Infusion of Different Doses of Esketamine on the Bispectral Index During Sevoflurane Anesthesia: A Randomized Controlled Trial.
ArticleKetamine
Effect of subanesthetic dose of esketamine on postoperative pain in elderly patients undergoing laparoscopic gastrointestinal tumor Surgery:A prospective, double-blind, randomized controlled trial.
ArticleKetamine
Comparison of the analgesic effect of dezocine and esketamine in combination with sufentanil respectively after laparoscopic cholecystectomy: a prospective randomized controlled study.
PreprintPsilocybin
Psilocybin Promotes Cell-Type-Specific Changes in the Orbitofrontal Cortex Revealed by Single-Nucleus RNA-seq
ArticleKetamine
Effects of adding low-dose esketamine to sufentanil and propofol sedation during cervical conization: a single-centre, randomized controlled trial.
ArticleKetamine
Supplemental low-dose esketamine to propofol versus propofol alone on perioperative characteristics in children undergoing surgery: a prospective randomized controlled trial.
ArticleKetamine
Efficacy and safety comparison of esketamine-propofol with nalbuphine-propofol for upper gastrointestinal endoscopy in children: a multi-center randomized controlled trial.
ArticleKetamine
Preoperative Esketamine Alleviates Postoperative Pain after Endoscopic Plasma Adenotonsillectomy in Children.
ArticlePsilocybin
Acute psilocybin increased cortical activities in rats.
ArticleKetamine
Efficacy and Safety of a Subanesthetic Dose of Esketamine Combined with Propofol in Patients with Obesity Undergoing Painless Gastroscopy: A Prospective, Double-Blind, Randomized Controlled Trial.
ArticleKetamine
Esketamine combined with pregabalin on acute postoperative pain in patients undergoing resection of spinal neoplasms: study protocol for a randomized controlled trial.
ArticlePsilocybin