The open index of psychedelic research

Open datasets, papers, preregistrations, and trials from across psychedelic science.

11,328 records6 sources
Showing 25–48 of 11,328
PreprintKetamine

Baseline Response Criterion and Changes in Emotional Bias as Markers of Esketamine Response in Treatment-Resistant Depression

Muh C, Favre P, Lutkenherm IK +3

Europe PMC2026
ProjectPsychedelics

Contexts, Risks, and Affordances among Autistic Adults Using Psychedelics for Therapeutic Purposes: A Naturalistic, Mixed-Methods Study

OSF2026
PreprintKetamine

Intranasal Esketamine for Treatment-Resistant Depression: A Practical Clinical Guide to Patient Selection, Dosing, Combination Strategies and Adverse-Event Management

De Berardis D, Barlattani T, Carano A +10

Europe PMC2026
PreprintPsilocybin

Group psilocybin in an integrative retreat setting enhances social connection: an observational case report

Rayford D, Dayal S, Boudreau K +3

Europe PMC2026
PreprintPsilocybin

Group psilocybin in an integrative retreat setting enhances social connection: an observational case report

Rayford D, Dayal S, Boudreau K +3

Europe PMC2026
PreprintKetamine

Efficacy and Safety of Intranasal Dexmedetomidine Combined with Esketamine for Premedication in Children Undergoing Laser Treatment for Burn Scars: A Randomised Self-Controlled Crossover Trial

S, Cao J, Liu P +2

Europe PMC2026
PreprintPsilocybin

Language-associated brain representations covary with disruption of selfhood under psilocybin

Cooper G, Stoliker D, Astl Delgado SV +6

Europe PMC2026
PreprintMescaline

Mescaline distribution and concentration in Trichocereus bridgesii

Engel L, Hall DR, Skene D +3

Europe PMC2026
PreprintPsilocybin

Quality of Life and the Case for Consent-Based Psilocybin Access – Questions on the Regulatory Framework and Cost

Ancans J

Europe PMC2026
PreregistrationPsilocybin

White Matter Microstructure and Psilocybin Treatment for OCD: Baseline Associations, Longitudinal Change, and Link to Symptom Response

OSF2026
PreprintKetamine

Neurite Complexity and Plasticity Markers Track Synaptic Vesicle Density in the Living Human Brain: A Multimodal PET-MRI-EEG Study

Agnorelli C, Peill J, Kurtin DL +25

Europe PMC2026
PreregistrationKetamine

Ketamine and Super Refractory Status Epilepticus in Adults: A Scoping Review

OSF2026
PreprintMDMA

Pharmacokinetic disposition in oral fluid, excretion profile, and subjective and physiological responses following oral and intranasal administration of Clophedrone (3-CMC)

La Maida N, Poyatos L, Trana AD +12

Europe PMC2026
PreprintKetamine

Dizocilpine-derived K2060 exhibits enhanced blockage at NMDA receptors with impaired Mg2+ block and provides strong protection against audiogenic seizures

Kolcheva M, Netolicky J, Misiachna A +14

Europe PMC2026
PreregistrationPsilocybin

U.S. Health System Readiness to Adopt Classic Psychedelic-Assisted Therapy for People with Serious Illness: A Scoping Review

OSF2026
PreprintKetamine

Clinical Effects of Low-Dose Esketamine During Emergency Conversion From Labor Epidural Analgesia to Category I Cesarean Section: A Randomized Controlled Trial of Maternal Hemodynamics, Analgesia, Sedation, and Neonatal Outcomes

Liang W, Zhai L

Europe PMC2026
PreprintPsychedelics

Are you “the medicine”? Intention category and explicitness as predictors of perceived outcomes associated with psychedelic experiences

Mosina I, Luke D

Europe PMC2026
PreprintPsilocybin

Psilocybin-Assisted Therapy for Existential Distress in Serious and Life-Limiting Illness: Emerging Trial Evidence, Barriers to Access, and the Case for Individualized Eligibility

Ancans J

Europe PMC2026
PreprintAyahuasca

Ayahuasca plant genomes reveal retrotransposon-derived centromeres and contrasting routes to DMT and β-carbolines

Qiu R, Mann SGA, Nascimento T +14

Europe PMC2026
PreprintPsychedelics

Serotonin <sub>2A</sub> receptors in the medial prefrontal cortex do not drive DOI-induced head-twitch responses in rodents

Vuruputuri RM, Reghunath V, Mukherjee S +4

Europe PMC2026
TrialKetamine

Ketadex Versus Ketofol for Adult Procedural Sedation in the Emergency Department.

ClinicalTrials.gov2026
PreprintPsilocybin

Molecular Mechanism of Psilocybin-Induced Longevity: The c-Fos–SIRT6 Epigenetic Axis

Lakshmanane B

Europe PMC2026
ArticleKetamine

Ketamine and esketamine during breastfeeding: a systematic review of human pharmacokinetic, infant and lactation outcomes.

Olivola M, Martiadis V, Prodi T +6

Europe PMC2026
ArticleKetamine

Subcutaneous Esketamine in Adolescents with Severe Depressive Episodes: A Five-Case Series.

Magalhães IPA, Lopes DN, Amato IA +6

Europe PMC2026