The open index of psychedelic research

Open datasets, papers, preregistrations, and trials from across psychedelic science.

11,281 records6 sources
Showing 1,441–1,464 of 11,281
ArticlePsilocybin

Classic psychedelics and personality: An updated systematic review.

Vicentini AB, de Paula CC, Silva Reis JA +3

Europe PMC2026
PreregistrationPsilocybin

From Amygdala to Synapse: A Multimodal Longitudinal RCT of Psilocybin-Assisted Therapy for Major Depressive Disorder Integrating Neuroplasticity Biomarkers, Inflammatory Indices, and Acute Experiential Mediators

OSF2026
ArticleKetamine

Safety and tolerance of oral ketamine: A systematic review.

Novaretti N, Pessoa RMP, Hallak JEC +2

Europe PMC2026
PreregistrationPsilocybin

The Therapeutic Alliance's Moderating Role on the Negative Relationship Between Dread of Ego Dissolution and Changes in Depression Symptom Severity in Psilocybin-Assisted Therapy for Treatment-Resistant Depression: A Secondary Analysis of the PsiDeR Trial.

OSF2026
PreregistrationMDMA

MDMA-Assisted Psychotherapy for Social Anxiety in Adults with Autistic Spectrum Disorder: A Randomized, Double-Blind, Placebo-Controlled Longitudinal Study

OSF2026
DatasetIbogaine

Tuning reductase activity in monoterpene indole alkaloid biosynthesis

Sarah O'Connor

Dryad2026
ProjectPsilocybin

From Amygdala to Synapse: A Multimodal Longitudinal RCT of Psilocybin-Assisted Therapy for Major Depressive Disorder Integrating Neuroplasticity Biomarkers, Inflammatory Indices, and Acute Experiential Mediators

OSF2026
TrialKetamine

Multimodal Pharmacological Study of Clinical Cohorts for Major Depressive Disorder

ClinicalTrials.gov2026
ArticlePsychedelics

Psychedelics do not always enhance cognitive flexibility: The potential role of time-varying effects on reward learning processes.

Kosted R, Doss MK, Donegan JJ +2

Europe PMC2026
ArticlePsilocybin

Psychedelic-induced hypomania and mania: a systematic review and meta-analysis.

Eskinazi M, Nasserdine R, Cusin RM +19

Europe PMC2026
ArticlePsilocybin

A systematic review of the pharmacokinetics of classical serotonergic psychedelic compounds in healthy adult subjects.

Hampsey E, Martin K, Kalfas M +5

Europe PMC2026
PreprintMDMA

The chicken and the egg - a systematic review of the relationship between recreational drug use and mental health in the general population

Clayden B, Abeywickrema M, Balaet M

Europe PMC2026
ArticleKetamine

Desflurane combined with ciprofol or esketamine improves postoperative symptoms without compromising early neurocognitive recovery after intracranial aneurysm endovascular coiling.

Wang T, Xing N, Li H +4

Europe PMC2026
ProjectMDMA

MDMA-Assisted Psychotherapy for Social Anxiety in Adults with Autistic Spectrum Disorder: A Randomized, Double-Blind, Placebo-Controlled Longitudinal Study

OSF2026
PreprintLSD

Lysergic acid diethylamide reverses aging- and neurodegeneration-associated brain transcriptional programs

Savino A, Liaci C, Bertani I +7

Europe PMC2026
ArticlePsilocybin

Effects of psilocybin on sleep quality and brain microstructure in chronic cluster headache.

Brendstrup-Brix K, Ozenne B, Fisher PM +10

Europe PMC2026
ArticleKetamine

Intramuscular Ketamine Pharmacokinetics in Humans: A Review.

Ananyev J, Myers TM

Europe PMC2026
ArticlePsilocybin

A spatiotemporal gating hypothesis for psilocybin plasticity: reconciling the 5-HT₂A-TrkB mechanistic paradox.

Pei G

Europe PMC2026
PreregistrationKetamine

Interventions delivered in healthcare settings or with the involvement of a health professional to support ketamine cessation in children and young people (under the age of 18 years): A scoping review protocol

OSF2026
ArticleKetamine

Differences in how NMDA antagonists modulate negative affective biases in male rats may serve as a predictor of clinical efficacy in major depressive disorder.

Hinchcliffe JK, Kamenish K, Bartlett J +3

Europe PMC2026
ArticlePsychedelics

A landscape analysis of psychedelic facilitation training in the US.

Palitsky R, Peacock C, Breau JA +2

Europe PMC2026
ArticlePsilocybin

Blinding integrity in psychedelic research: Evidence from a comparative randomized controlled trial of psilocybin, MDMA, and methylphenidate in healthy volunteers.

Belinger L, Rieser NM, Engeli EJE +8

Europe PMC2026
ArticlePsilocybin

Psilocybin-induced neurocardiogenic syncope: a case report.

Atiq MA, Weisman E, Guerra RB +5

Europe PMC2026
ProjectKetamine

OMS-KAT-001 · Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD

OSF2026